Weakened Immune System
Individuals with a weakened immune system have a higher chance of developing septic arthritis. Patients with kidney problems, liver problems, diabetes, immune-weakening viruses, and individuals taking immunosuppressants are in this increased risk category. Joints are already susceptible to germs and infection even in cases where the individual is healthy. When the joint becomes infected and the immune system can't destroy the infection, the condition just continues to worsen. The infection eats away at the joint and surrounding tissues. Joint cavities are small and enclosed, so infections can cause a huge amount of damage in very little time. While immune responses can contribute to joint damage, individuals with weakened immune systems will have infections that spread more rapidly. Delayed treatment can cause permanent joint damage and degeneration.