An elevated body temperature or fever is an adaptive response produced by the brain when harmful pathogens are present in the body. This response is triggered to create an inhospitable or unfavorable environment for the harmful bacteria, virus, parasite, or fungus affecting the individual. A fever can manifest in a hemolytic uremic syndrome patient because many cases are caused by an infection with certain types of viruses and bacteria. Bacteria known to induce fever-producing hemolytic uremic syndrome include E. coli, S pneumoniae, salmonella typhi, campylobacter jejuni, Yersinia pseudotuberculosis, Neisseria meningitides, legionella pneumophila, and mycoplasma species. Viruses known to induce fever-producing hemolytic uremic syndrome include human immunodeficiency virus, coxsackievirus, echovirus, influenza, Epstein-Barr, herpes simplex, and herpesvirus 8. When any of these viruses or bacteria enter the body, colonize, and induce hemolytic uremic syndrome, a healthy immune system will respond by raising the body temperature and producing a fever.
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