Familial Hypercholesterolemia Treatment Guide
Familial hypercholesterolemia is a genetic condition that causes elevated levels of low-density lipoprotein (LDL) cholesterol in the body. Patients with this disorder have a high risk of developing cardiovascular disease, and they often experience heart attacks at a younger age than the general population. In fact, research has shown patients with familial hypercholesterolemia have five times the risk of cardiovascular disease compared to individuals with cholesterol levels less than 130mg/dL. Men with this condition develop cardiovascular disease an average of twenty years earlier than those at normal risk, and some of these men may even have heart disease in their twenties. For women with familial hypercholesterolemia, cardiovascular disease appears as much as thirty years earlier than it does in women without this condition. In addition to elevated cholesterol, common symptoms of familial hypercholesterolemia include cholesterol deposits on the skin, eyelids, tendons, and cornea. These deposits usually have a waxy appearance. Some patients with this disease may experience chest pain (angina). A simple blood test is all that is needed to diagnose familial hypercholesterolemia.
Since this condition drastically increases the risk of a cardiovascular event, treatment focuses on heart health and reducing cholesterol as much as possible. The treatments and lifestyle modifications described below are some of the most common recommendations for patients with familial hypercholesterolemia.
Get More Physical Exercise
Exercise improves cholesterol and reduces the risk of cardiovascular disease. Doctors recommend that everyone with familial hypercholesterolemia get more physical exercise, and exercise is the preferred first treatment for children with this condition. Before beginning an exercise routine, patients should consult their doctor for a physical examination and advice on the most appropriate routine for their individual needs. Generally, patients are advised to aim for 150 minutes of moderate exercise each week. Brisk walking, aerobics, yoga, swimming, dancing, and even household chores can all count. While exercising, patients should be vigilant for any signs of chest pain, dizziness, shortness of breath, or nausea. If these signs appear, the patient should stop exercising and schedule a doctor's appointment. Patients who are new to exercise should start with ten minutes a day, gradually increasing this to thirty minutes over a period of several weeks. Joining an exercise class or working with a personal trainer may be beneficial for some patients.
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Maintain A Healthy Weight
Being overweight or obese further increases the already elevated risk of heart disease for patients with familial hypercholesterolemia, which is why maintaining a healthy weight is important as treatment. Currently, many doctors use body mass index (BMI) as a tool to determine a healthy weight range for individual patients. This measurement is a ratio of height to weight. A BMI of between 18.5 and 24.9 is considered optimal. Readings of between twenty-five and 29.9 are considered overweight, and readings of thirty or more are classified as obese. To maintain a healthy weight, patients are encouraged to exercise regularly and pay attention to their nutrition. Minimizing fast food, fried foods, and red meat can help, and patients should also try to include more fruits and vegetables in their meals. Some patients have found adopting a primarily plant-based diet is beneficial for weight control. For patients who have serious struggles with weight, medication or surgical intervention may be appropriate.
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