10 Potential Causes And Risk Factors For An Enlarged Spleen

Lisette Marie

7. Leukemia: Blood Cancer's Hidden Impact

Bald Woman Receiving Chemotherapy Treatment. Photo Credit: Envato @seventyfourimages

Similar to lymphoma, various types of leukemia, particularly chronic leukemias (like CML or CLL), frequently cause splenomegaly. This occurs when cancerous white blood cells proliferate excessively in the bone marrow and then spill into the bloodstream and organs, including the spleen. The spleen then swells as it attempts to filter these abnormal cells. This enlargement can be a key diagnostic clue, often accompanied by other subtle symptoms like fatigue, unexplained bruising, or recurrent infections, signaling a serious underlying blood cancer demanding urgent hematological assessment.

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7. Leukemia: Blood Cancer's Hidden Impact

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