5 Abdominal Pain Warning Signs
Upper Abdomen Pain

Upper abdominal pain may be an indication of liver problems such as hepatitis (inflammation of the liver). Pain in the upper abdomen may also be associated with gallstones, pneumonia, or a heart attack. The combination of upper abdominal pain and nausea may be a sign of heartburn or acid reflux. Pain located in the upper abdominal area may also indicate an enlarged spleen, hard stool that cannot be passed, or an injury.