A female doctor works at a desk in hospital,discussing kidney failure and chronic kidney disease. Photo Credit: Envato @nansanh
While the spotlight often falls on acetaminophen’s impact on the liver, its potential to harm kidney health is equally concerning. Chronic use of acetaminophen has been associated with an increased risk of kidney damage, particularly when combined with other analgesics or in individuals with pre-existing renal conditions. The kidneys, responsible for filtering waste from the blood, are vulnerable to nephrotoxicity from long-term exposure to acetaminophen’s byproducts. Over time, this can lead to reduced kidney function or even chronic kidney disease. Signs of impaired kidney function, such as swelling, changes in urination, or fatigue, often develop gradually, making early detection difficult. People with diabetes, high blood pressure, or advanced age may face heightened vulnerability. To protect kidney health, patients should avoid exceeding recommended doses, stay hydrated, and consult with a healthcare provider, especially if they require long-term pain management or have underlying health issues.