Tips For Treating Pick's Disease
Pick's disease, also called frontotemporal dementia, is a rare genetic disorder and form of dementia that most often affects individuals younger than sixty-five years old. Typically, the condition affects behavior, personality, judgment, and language skills. Symptoms include drastic mood swings, repetitive behaviors, social withdrawal and isolation, depression, lack of empathy, and being impulsive. A definitive diagnosis of this disease is made through blood tests, neurological examinations, brain scans, speech tests, and interviews with family members. The average life expectancy is between two to seven years after diagnosis, and some individuals live for a decade. Pick's disease cannot be cured, and treatments are used to manage symptoms. The interventions described below can help Pick's disease patients improve their quality of life.
Antidepressant Medication
Antidepressants help reduce the aggression, irritability, loss of interest, and withdrawal that are common with Pick's disease. They can benefit patients by calming them and flattening out mood swings so they are less drastic. For patients with Pick's disease, doctors typically choose to start with drugs known as selective serotonin reuptake inhibitors (SSRIs). SSRIs are a type of antidepressant that increases levels of the hormone serotonin in the brain. Citalopram, fluvoxamine, sertraline, and fluoxetine are SSRIs patients generally tolerate well. Possible side effects include fatigue, dry mouth, nausea, and dizziness. Patients taking antidepressants should be monitored closely by their doctors for any mood changes or suicidal thoughts. Occasionally, they may cause a fast heartbeat, and any cardiac concerns should be reported to the healthcare professional who put the patient on the medication originally.
When switching from one antidepressant to another, adding additional antidepressants to an active treatment regimen, or stopping an antidepressant, patients and their doctors should work together to taper the dosages on a gradual schedule. Discontinuing an antidepressant suddenly can result in unpleasant withdrawal symptoms such as vivid dreams, insomnia, muscle aches, chills, tingling sensations, and a recurrence of depression symptoms.
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Antipsychotic Medication
Like antidepressants, antipsychotic medications can help Pick's disease patients by calming them. In fact, many antipsychotic medications have a sedating effect, and they are also helpful in stabilizing mood, reducing mania, impulsive behavior, and aggression. Some of the most commonly used antipsychotics include aripiprazole, cariprazine, lurasidone, and risperidone. Side effects are similar to those of antidepressants and include drowsiness, dizziness, weight gain, constipation, increased blood sugar, and blurred vision. Severe side effects, such as muscle spasms, seizures, fainting, and fever may occur, and these should be reported to a doctor promptly. Sometimes, several antipsychotic medicines may be used at one time to provide better symptom control. Patients who are on a combined drug regimen should be monitored very closely by their medical team. If some antipsychotics cause intolerable side effects, other forms of medication can be tried.
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