Physicians may also recommend medication for patients diagnosed with acquired hemolytic anemia. One category of medications often used are corticosteroids, which are typically the first line of attack utilized when beginning to treat acquired hemolytic anemia. These are powerful steroids that stop the immune system from creating the antibodies destroying red blood cells. However, steroid use is never recommended as a long-term solution to any health problem due to the seriousness of the potential side effects. These corticosteroids are typically utilized in conjunction with another treatment option to minimize the risk of causing further complications.