Reactive arthritis results in painful swelling in the joints, most often the knees or ankles. The heels, toes, and fingers also swell and patients often have persistent lumbar pain that is worse in the morning or at night. The eyes may be red and irritated, and patients may have a rash on the soles of their feet or their palms and burning urination. While the ultimate cause of reactive arthritis is unknown, reports indicate a genetic predisposition comes into play. Research also shows reactive arthritis most often occurs after a variety of infections, including Chlamydia trachomatis, shigella, Campylobacter bacteria, and salmonella. Reactive arthritis appears about a month after the person experiences symptoms of their infection. Reactive arthritis used to be considered Reiter's syndrome, though the two are now classified as different conditions.
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