[caption id="attachment_4929" align="aligncenter" width="2124"]
Fatigue is a common symptom in many autoimmune diseases because the body is working overtime in the wrong direction. Instead of protecting the body from foreign cells, it mistakes healthy tissue and organs as being invaders, which prompts an attack or flare-up. When healthy cells, tissues or organs are under attack, it disrupts proper functioning and creates fatigue. Lack of appetite and poor nutrition during a flare may also cause fatigue.