A large number of familial adenomatous polyposis patients have polyps develop in the duodenum, which is the first portion of the small intestine, placed immediately after the stomach. Studies conducted on familial adenomatous polyposis patients indicated between thirty and seventy percent of them had duodenal polyps at any given time. Over a patient's lifetime, the risk of developing these polyps becomes almost one hundred percent. The polyps eventually turn into cancerous adenomas, and when patients don't receive treatment for their disease, the leading cause of death is colorectal cancer. However, the second leading cause of death is cancer of the duodenum. Familial adenomatous polyposis patients have a risk of developing duodenal cancer that's one hundred to 330 times higher than the general population. The average age at which duodenal cancer develops is about fifty-two years old.
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