Seizures are a serious sign something is wrong with the brain. They are a common early symptom of Leigh's disease. Seizure activity happens because Leigh's disease causes lesions in many parts of the brain, including the cerebral cortex. These lesions cause the neurons in the brain to behave abnormally, which leads to a seizure. A seizure usually lasts for two minutes or less. It can have many different manifestations, which may or may not include convulsions. Regardless of the type of seizure, the child will lose consciousness briefly. Sometimes, the only symptom of a seizure is a very brief loss of awareness; this is called an absence seizure.
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