One of the most common treatments for joint pain, inflammation, and allergic reactions in a specific area of the body is to receive cortisone injections. Cortisone is a steroid which can be taken orally, applied to the skin, or injected. Because cortisone injections provide near-instant relief and can last for months, they have become the go-to treatment for arthritis and other inflammatory joint conditions. However, these injections can have horrible side effects, making them a somewhat risky endeavor.
Cortisone belongs to a broad class of medications known as corticosteroids. These medications and other steroids have been found to cause a variety of mood changes in some individuals. While these mood changes are usually minor, sometimes they can be quite serious. Typically mood-related side effects include irritability, anxiety, memory loss, and difficulty concentrating. In some rare cases, however, more serious effects have been reported including paranoia, delusions, or depression. The risk and severity of any mood changes depends on the dosage of cortisone administered.