Health Benefits Of Retinoids
A retinoid is a synthetic derivative of a group of fat-soluble vitamins found in eggs, sweet potatoes, and carrots or that are referred to as vitamin A. Retinoids have numerous essential functions in an individual's body, such as roles in the regulation of cell proliferation, vision, cell differentiation, bone tissue growth, activation of tumor suppressor genes, and immune function. There are three different retinoid generations. First-generation retinoids are retinal, isotretinoin, alitretinoin, retinol, and tretinoin. Second generation retinoids are acitretin and etretinate. Third generation retinoids include bexarotene, adapalene, and tazarotene. The main use of retinoids in modern-day medicine is the regulation of the growth of an individual's epithelial cells. Epithelial cell regulation can be helpful for many skin conditions and diseases.
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Helps With Acne
Retinoids can be used in the forms of topical gels, creams, ointments, and foams to help control comedonal and cystic acne. The mechanisms that have been identified to cause these types of acne include abnormal desquamation of the skin cells, the proliferation of keratinocytes, pilosebaceous canal obstruction, androgen-driven excess sebum production, inflammation, and altered immune system activity in an individual's body. Topical retinoids work by blocking numerous inflammatory pathways known to cause whiteheads and blackheads in the hair follicles. Retinoids also act to renormalize desquamation or the normal and effective shedding of dead skin cells. Retinoids also help unblock the clogged follicles that produce whiteheads and blackheads. Retinoids can decrease the release of inflammatory cytokines and nitric oxide, which stops the process of inflammation in the skin that produces the redness typically seen with comedonal and cystic acne.
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Reduces Wrinkles And Fine Lines
Retinoids may be used by some individuals to help reduce the appearance of wrinkles and decrease the frequency of fine lines on the face. Wrinkles and fine lines form as an individual becomes older, their skin loses its elasticity, and it decreases in overall strength. As an individual gets older, their skin begins to lose its ability to retain moisture properly, becomes drier, and eventually thins out. These mechanisms cause the molecules of collagen in the skin to crack apart and then clump together, which is what forms wrinkles and fine lines on the surface of the skin. Retinoids are thought to help reverse this aging process of the skin by promoting and increasing the production of collagen. Retinoids are also known to promote the formation of tiny new blood vessels in the skin, which helps with skin color and the retention of moisture. Retinoids also help fight the formation of fine lines and wrinkles by increasing the turnover speed of superficial skin cells, helping reveal the layer of cells underneath that takes the place of dead skin cells.
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