What Is Comhist?

Comhist is a medication used to relieve the symptoms of upper respiratory infections. It belongs to a class of medications known as antihistamines, and it is available over-the-counter and by prescription. Comhist is a combination of chlorpheniramine and phenylephrine, and it is also sold as a combination of chlorpheniramine and phenyltoloxamine. The medication is frequently used to treat the symptoms of allergies, sinusitis, bronchitis, and the common cold. Patients who use Comhist may develop side effects, including headaches, dizziness, and constipation. In general, this medicine should not be given to children under six years old, and it should never be used to make a child sleepy.

The uses, side effects, precautions, and potential medication interactions associated with Comhist are discussed below.

How It Works


As an antihistamine, Comhist works by physically blocking the H1 receptors in the body so histamine cannot bind to them. The body makes histamine in several areas, and large quantities of histamine are made in the mast cells of the skin, nose, and throat. These areas frequently come into contact with the outside environment, and histamine plays a role in the body's immune response. Histamine is released by the mast cells if the body detects a foreign substance, and this release can produce itching, swelling, and redness. In cases of allergies, the body often releases much more histamine than it should, and this produces watery eyes and other symptoms. Antihistamines like Comhist work to calm this overreaction. In addition to Comhist, other types of antihistamines include loratadine, alimemazine, hydroxyzine, promethazine, fexofenadine, and acrivastine.

Get the full details on the uses and benefits linked to Comhist next.

Emily Fowler