A small zit here and there usually is not a problem for most individuals, but when serious eruptions arise, acne can be a debilitating condition. Thankfully, there are many acne treatments available, one of which is an injection of cortisone. When injected, cortisone zaps the acne in one quick step. The one-time treatment can get rid of a pimple completely in one or two days, though at the very least it can help reduce the size and redness of the mark. Cortisone is injected directly into the center of a pimple and only feels like a minor pinch. There are no restrictions following treatment, and normal activity can resume immediately.