Guide To Cyclosporine

Potential Side Effects

Cyclosporine can cause mild to severe side effects. They can differ based on how it is administered. Common side effects of the oral and injectable forms include high blood pressure, low magnesium levels, tremors, gum overgrowth, excessive hair growth, and blood clots within the kidneys. Nephrotoxicity, when there are excess toxins within the kidneys, is a common side effect of this medication when it is taken in large doses or over long periods. Less common side effects include liver damage, kidney damage, and lung problems. Although they are not as common, they are more serious.

Vasoconstriction, which is the narrowing of blood vessels, is one side effect that can lead to many of these other damaging effects. As an eyedrop solution, cyclosporine can cause side effects relating to the eyes. Examples include burning, itching, dryness, or redness. Since it is an immunosuppressant, individuals taking this drug may also be at an increased risk of infections, regardless of which form they are taking.

Precautions To Remember

Seniors, as well as individuals with pre-existing kidney disease or hypertension, should consult their doctor about taking cyclosporine. This is because they may be at an increased risk of kidney damage. Those taking creatine supplements may also be at risk because cyclosporine can cause increased creatinine levels in the blood, which can overburden the kidneys. When taking this medication, individuals should not drink alcohol. Doing so can result in both liver and kidney damage.

Those who have any form of liver disease are not only at risk of liver damage when taking cyclosporine, but other complications as well. Impaired liver function can slow the time it takes for the body to metabolize this medication. This can then lead to excessive amounts of the medication within the liver and body. Also, as cyclosporine is an immunosuppressant, individuals with any active infections should avoid taking it as well. Those taking this medication should also avoid others who may be sick with viral, bacterial, or fungal infections for the same reason.