Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. The medication is available as a tablet and an oral solution. Adults with high blood pressure will be placed on an initial dose of up to ten milligrams daily. The standard maintenance dose is between twenty to forty milligrams. Patients with kidney or liver issues may need a lower dose.
Lisinopril is an effective medication for high blood pressure. Of course, patients will still need blood pressure checks when taking this medication. It is also an option for heart failure treatment in some patients. Some diabetes patients will benefit as well, though they will still need to conduct blood sugar checks and follow other treatments their doctor prescribes.
How It Works
Like other ACE inhibitors, lisinopril blocks an enzyme that converts angiotensin I into angiotensin II. This reduces angiotensin II in the blood. It makes it less effective. The blood vessels can relax, and the heart receives more blood and oxygen. Additionally, ACE inhibitors reduce the amount of aldosterone released by the adrenal cortex. This mechanism helps the kidneys release sodium that is excreted through urination. Lisinopril is the only medication in its class that the liver does not metabolize. It is unique because it is a water-soluble ACE inhibitor. This medicine has a half-life of approximately twelve hours.
Continue reading to learn about the uses and benefits next.