Patients might also think about taking some antidepressants for hypersomnia. While these medications are typically designed to treat depression, they are also effective at helping patients manage their sleeping disorders like hypersomnia. The types of antidepressants most commonly used for treating hypersomnia include those of fluoxetine, sertraline, citalopram, and paroxetine. While each of these medications operates slightly differently when consumed, they all work on combating depression by improving an individual's sleep and energy levels. These medications work by restoring the balance of serotonin in the brain, a natural chemical that contributes to feelings of happiness and well-being. Serotonin controls and modulates such processes in the brain as memory, cognition, reward, and learning processes. When this chemical is at the proper levels, an individual's sleep should be more balanced. These medications are typically designed to be taken on a daily basis. Once a patient's energy levels have started to improve, they should have fewer difficulties in staying awake.