10 Potential Causes And Risk Factors For An Enlarged Spleen

6. Lymphoma: The Spleen's Cancerous Swelling

Thyroid model with pill drug treatment, Hyperthyroidism, Overactive or Lymphoma. Photo Credit: Envato @chormail

Beyond general blood clots, lymphoma – a cancer of the lymphatic system – is a significant and often insidious cause of an enlarged spleen. The spleen is rich in lymphatic tissue, making it a common site for lymphoma cells to accumulate and proliferate. This growth can lead to palpable enlargement, which might be the first, albeit subtle, sign of the cancer. Unlike some other causes, the spleen may be enlarged due to direct cancerous infiltration rather than just increased workload, making it a critical warning sign demanding immediate oncological investigation.

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