10 Potential Causes And Risk Factors For An Enlarged Spleen

8. Sarcoidosis: Systemic Inflammation's Splenic Touch

Female doctor holding Lungs in hand on right side.Healthcare hospital service concept stock photo. Photo Credit: Envato @nuttapong_mohock

Sarcoidosis, a baffling inflammatory disease, can ingeniously cause an enlarged spleen. This condition involves the growth of tiny, inflammatory cell clusters (granulomas) in various organs, including the spleen. While sarcoidosis often affects the lungs and lymph nodes, splenic involvement is common, leading to enlargement as the spleen's tissue is infiltrated. This non-infectious, systemic inflammation can lead to a palpable spleen, often without other obvious symptoms, making it a subtle but crucial warning sign of a widespread inflammatory disorder.

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