10 Serious Indicators Of Wernicke's Encephalopathy

9. Peripheral Neuropathy (New or Worsening)

Thiamine is essential for healthy nerve function throughout the body. Therefore, a sudden onset or rapid worsening of peripheral neuropathy – nerve damage outside the brain and spinal cord – can be a serious indicator. Symptoms might include unexplained numbness, tingling, burning sensations, or weakness in the extremities (hands and feet). While many conditions cause neuropathy, its acute appearance alongside other neurological symptoms like ataxia or confusion should strongly raise suspicion for Wernicke's encephalopathy, signaling widespread thiamine deficiency.