10 Symptoms That May Indicate Large Cell Carcinoma

Lisette Marie

7. Unexplained Weight Loss and Loss of Appetite

Feet of an Asian woman on a weight scale. Photo Credit: Envato @cait00sith

Significant and unexplained weight loss, even without trying, coupled with a decreased appetite, can be an insidious red flag for large cell carcinoma. This symptom, sometimes part of paraneoplastic syndrome, occurs because cancer cells can increase the body's metabolic rate, burning more calories, while also releasing substances that suppress appetite. Patients may notice their clothes fitting looser or a general disinterest in food. This "cancer cachexia" is often progressive and can severely impact a patient's strength and ability to fight the disease, making any unprompted weight loss a symptom to discuss with a doctor immediately.

8. Hoarseness or Voice Changes

Closeup of woman touch sore throat. African female suffer from swallowing difficulty, angina or cold. Photo Credit: Envato @Dimaberlin

A persistent change in voice, such as hoarseness, that doesn't resolve after a few weeks, can be a subtle but important indicator of lung cancer, including large cell carcinoma. This symptom arises if a tumor in the lung grows and presses on the recurrent laryngeal nerve, which controls the vocal cords. The pressure on this nerve can interfere with its function, leading to a weak, breathy, or raspy voice. While hoarseness is commonly associated with colds or allergies, a prolonged or unexplained change warrants medical evaluation, as it could signal a more serious underlying issue.

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7. Unexplained Weight Loss and Loss of Appetite

8. Hoarseness or Voice Changes

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