10 Unmissable Signs You Might Have Ataxia-Telangiectasia - No Doctor's Appointment Needed

9. Increased Risk of Cancers (Especially Leukemias and Lymphomas)

A-T is tragically linked to an increased predisposition to certain cancers, particularly leukemias and lymphomas, often developing in childhood or adolescence. This heightened risk stems from the faulty ATM gene's role in DNA repair; without proper repair mechanisms, cells are more prone to uncontrolled growth. While a cancer diagnosis is obviously severe, understanding this association in the context of other A-T symptoms can sometimes lead to earlier screening or more targeted diagnostic investigations.

10. Sensitivity to Radiation (Medical and Environmental)

A surprising, yet critical, indicator related to the ATM gene's function is an unusual sensitivity to radiation. Individuals with A-T are highly sensitive to ionizing radiation, including medical X-rays, CT scans, and radiation therapy, which can cause significant damage to their cells. This sensitivity is a vital diagnostic clue and a critical consideration for medical management. Awareness of this unique vulnerability can prevent unnecessary harm and guide safer diagnostic and treatment protocols.