11 Unbelievable Reasons Your Kidneys Might Be Throwing a Fit: Glomerulonephritis Edition

7. Goodpasture Syndrome

Goodpasture syndrome, an autoimmune disease, causes the immune system to mistakenly attack the kidneys and lungs. It often results in glomerulonephritis due to the development of anti-glomerular basement membrane (anti-GBM) antibodies. Symptoms can include blood in the urine, coughing up blood, fatigue, and swelling in the legs. Diagnosis involves blood tests to detect anti-GBM antibodies, urine tests, and imaging studies of the lungs and kidneys. Treatment typically includes plasmapheresis to remove harmful antibodies and immunosuppressive medications, such as corticosteroids and cyclophosphamide, to control inflammation. Prompt treatment can help prevent irreversible kidney damage and respiratory complications.

8. Diabetic Nephropathy

Diabetic nephropathy, a complication of chronic diabetes, is a leading cause of glomerulonephritis and kidney failure. High blood sugar levels damage the glomeruli over time, leading to protein leakage in the urine (albuminuria). Patients often experience swelling in the extremities, frequent urination, and high blood pressure. Diagnosing diabetic nephropathy involves monitoring blood sugar levels, blood pressure, and regular urine and blood tests to assess kidney function. Treatment focuses on controlling blood sugar and blood pressure through medications such as ACE inhibitors or ARBs, alongside lifestyle changes like a balanced diet, exercise, and weight management. Early intervention can significantly slow disease progression.