11 Unbelievable Reasons Your Kidneys Might Be Throwing a Fit: Glomerulonephritis Edition

9. Hemolytic Uremic Syndrome (HUS)

Hemolytic uremic syndrome (HUS) is a rare but serious condition that can cause acute glomerulonephritis. Often triggered by bacterial infections like E. coli, HUS leads to the destruction of red blood cells and clogs the kidneys' filtering system. Symptoms include bloody diarrhea, decreased urination, fatigue, and swelling in the hands and feet. Diagnosis involves blood tests to detect anemia and kidney function, along with stool tests to identify bacterial infections. Treatment includes supportive care, such as IV fluids and blood transfusions, and, in severe cases, dialysis to support kidney function. Prompt medical attention is critical to prevent long-term kidney damage.

10. Post-Infectious Glomerulonephritis (PIGN)

Post-infectious glomerulonephritis (PIGN) typically develops after infections such as strep throat or impetigo. The immune response to the infection can create immune complexes that lodge in the glomeruli, causing inflammation. Symptoms include dark or red urine, swelling in the face or extremities, and high blood pressure. Diagnosis requires urine tests, blood tests for kidney function, and tests for recent infections, such as ASO titers for strep. Treatment focuses on resolving the underlying infection with antibiotics and managing symptoms like high blood pressure and swelling with diuretics and antihypertensives. Most patients recover fully with proper care.