15 Clear Warnings Your Body Might Be in Serotonin Overdrive

5. High Fever

A high fever is one of the most characteristic symptoms of severe serotonin syndrome. Fevers tend to occur because the overproduction of serotonin causes a loss of ability to regulate body temperature, which leads to an overall rise in core temperature. Any fever above 104 degrees Fahrenheit is generally considered high. Individuals with high fevers are often experiencing hyperthermia, an increase in body temperature that can potentially lead to organ damage. These patients need to seek emergency medical care immediately. It's important to tell the doctors about any medications they've taken, especially new doses. For doctors, one of the key signs that separates serotonin syndrome from other hyperthermic disorders is the shivering. If the condition isn't treated, the neurological conditions may progress to seizures and total unconsciousness.

6. Dilated Pupils

Dilated pupils, also known as mydriasis, can be one of the more visible signs of serotonin syndrome, signaling an overactive autonomic nervous system. Serotonin affects many involuntary bodily functions, and an excess can disrupt the delicate balance of these systems. When serotonin levels rise too high, the muscles controlling the pupils become overstimulated, causing them to expand. Dilated pupils can also increase sensitivity to light, making bright environments uncomfortable or even painful. This symptom is often accompanied by other neurological or physiological signs, such as restlessness, rapid heart rate, or muscle twitching. Although dilated pupils can result from a variety of causes, their presence alongside other symptoms of serotonin syndrome provides an important visual clue that serotonin levels may be elevated. If you notice persistently enlarged pupils and additional signs after a medication adjustment, consult a healthcare provider immediately to rule out serotonin syndrome.