15 Clear Warnings Your Body Might Be in Serotonin Overdrive

13. Excessive Sweating

Excessive sweating, also called hyperhidrosis, is a classic symptom of serotonin syndrome caused by the body’s inability to regulate temperature effectively. The overstimulation of serotonin receptors disrupts the hypothalamus, the brain’s temperature control center, leading to sweating that can be profuse and unrelated to environmental conditions. This symptom is often paired with other signs of dysregulation, such as fever or chills. Excessive sweating can quickly result in dehydration, further complicating the condition. If heavy sweating occurs alongside neurological symptoms, such as agitation, tremors, or confusion, it may signal that serotonin syndrome is progressing. Medical attention is essential to prevent the condition from becoming more severe.

14. Hyperreflexia (Overactive Reflexes)

Hyperreflexia, or exaggerated reflex responses, is a telltale neuromuscular symptom of serotonin syndrome. This occurs when serotonin overstimulates the spinal cord and peripheral nerves, causing reflexes to become overly sensitive. For example, a slight tap on the knee during a reflex test may result in an unusually forceful or prolonged response. This heightened reflex activity often coincides with other muscle-related symptoms, such as twitching, rigidity, or tremors. While hyperreflexia may seem less alarming than other symptoms, it’s a clear indication that the nervous system is in overdrive. Recognizing this sign early, especially after a recent medication change, can prompt timely medical intervention to address the underlying serotonin imbalance.