15 Ways To Effectively Treat Meralgia Paresthetica

5. Tricyclic Antidepressants

Tricyclic antidepressants have the potential to help relieve pain in many medical conditions, including meralgia paresthetica. Different medications have slightly different side effects, but some typical side effects include constipation, dry mouth, and drowsiness. These medications affect the levels of neurotransmitters in the body, which are created by nerves to help send messages to other nerves throughout the body. A tricyclic antidepressant increases the levels of serotonin and norepinephrine in the body. In addition, they block acetylcholine, an additional neurotransmitter. Acetylcholine causes the contraction of muscles and allows the nerves to send pain signals. By blocking and reducing the amount of acetylcholine in the body, the nerves fail to send as many pain signals as usual. Doctors may pair one of these antidepressants with an anticonvulsant medication to further reduce pain.

6. Physical Therapy

Targeted physical therapy can ease meralgia paresthetica by strengthening nearby muscles and reducing pressure on the affected nerve. A trained physical therapist may introduce gentle stretching, posture correction, and nerve gliding techniques to relieve symptoms. Core and hip exercises often help improve alignment and mobility, minimizing nerve compression in the pelvis. Therapy can also address gait abnormalities or muscular imbalances that aggravate the nerve. Patients should avoid aggressive exercises that worsen the condition. Over time, consistent therapy not only reduces pain but also restores function. It’s a long-term, non-invasive option—ideal for those looking to avoid injections or medication.