18 Hidden Causes of High Neutrophil Counts That Doctors Want You to Know

13. Chronic Sleep Deprivation

A good night's sleep does more than just help you feel rested—it plays a critical role in regulating immune function. Studies have found that chronic sleep deprivation can lead to increased neutrophil counts, a lesser-known consequence of poor sleep habits. When the body is consistently deprived of rest, it experiences a heightened stress response, leading to the release of stress hormones such as cortisol. These hormones signal the bone marrow to produce more neutrophils, resulting in a form of low-grade inflammation that persists over time. Individuals who regularly get insufficient sleep may not only experience fatigue and cognitive issues but also unknowingly alter their immune system balance. Interestingly, once proper sleep patterns are restored, neutrophil levels tend to return to normal. This highlights the importance of quality sleep in maintaining immune health and preventing unnecessary inflammatory responses in the body.