20 Cause of Petechiae and What You Need to Know About Them

16. Kawasaki Disease

Kawasaki disease is a rare inflammatory illness that primarily affects children under five. It causes blood vessel inflammation throughout the body, often leading to a high fever, swollen hands and feet, red eyes, and cracked lips. Petechiae may appear along with a widespread rash, particularly in the early stages. While the exact cause is unknown, the condition can lead to serious heart complications if not treated promptly. Diagnosis is clinical and often confirmed with blood tests and echocardiograms. Intravenous immunoglobulin (IVIG) is typically used to reduce inflammation. Petechiae in this context are more than skin-deep—they're vascular alarms.