Surprising Triggers Behind Pesky Muscle Cramps

17. Cirrhosis

Cirrhosis is a disease that kills the cells in the liver, resulting in scarring and eventual failure of the organ. It is most often caused alcohol abuse and hepatitis B and C, but there are many other causes for the disease as well. Many individuals with this disease experience leg cramps to a varying degree. While the cause is not completely certain, research indicates nerve damage and a decrease in the body's ability to metabolize energy may be at the root of the problem. Individuals with cirrhosis can find relief from muscle cramps in various forms, including prescription muscle relaxants as well as vitamin E supplements.

18. Restless Leg Syndrome (RLS): Beyond Just "Jumping" Legs

Often dismissed as simple fidgeting, Restless Leg Syndrome (RLS) is a neurological disorder characterized by an irresistible urge to move the legs, often accompanied by uncomfortable sensations like crawling, tingling, or, yes, cramping. These sensations typically worsen during periods of rest or inactivity, especially at night. Unlike a common cramp that resolves, RLS symptoms are relieved by movement, creating a vicious cycle of discomfort and disrupted sleep, which can lead to persistent muscle tension and subsequent cramping.