Causes & Risk Factors Of Fraser Syndrome

Condition Statistics

Condition statistics claim both boys and girls are equally at risk of being born with Fraser syndrome. There are about 250 cases of Fraser syndrome in the world, and in Europe, it is seen in one out of 500 thousand births, including babies who die at birth or before birth. Geneticists believe every human has mutated genes, and they do not know the risk factors that would cause gene mutations that lead to Fraser syndrome. However, they have seen parents who are closely related have a higher risk of passing the mutated genes down to their offspring.

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Affected Populations

Interestingly, Fraser syndrome is mostly seen in babies of the Roma people, who are also known as gypsies. These are individuals found in the eastern and southern parts of Europe. Some even live in America. They are believed to have originated on the Indian subcontinent and left many centuries to go to find work in the Middle East, and from there, they migrated into Europe. Traditional Roma individuals are expected to marry within their tribe. Because of this, the husband and wife might be close relatives, which puts them at greater risk for having a child who may contract Fraser syndrome and other autosomal recessive genetic diseases.

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