Causes Of Congenital Insensitivity To Pain

Autosomal Recessive Inheritance

Congenital insensitivity to pain occurs through autosomal recessive inheritance of the mutated gene. This means the individual with the disorder inherits a copy of the gene mutation from each of their parents. Although their parents are carriers of the gene mutation, because they only have one copy, they are typically healthy and do not present any symptoms or report any issues from the disorder. With the inheritance of a copy of the mutation from each parent, the disorder is then activated in the child, leading to the onset of symptoms at birth and continue throughout the child's life.

Continue reading to learn about how congenital insensitivity to pain is diagnosed.