Guide To The Symptoms Of Guillain-Barre Syndrome
Severe Pain

Severe pain is a relatively common symptom in the population of Guillain-Barre syndrome patients. Pain is typically known to manifest a couple of weeks before the onset of any muscle weakness. The exact pathophysiology of this symptom manifestation in Guillain-Barre syndrome is not clear, but it is thought to be associated with abnormalities in an affected individual's sensory nerve fibers and how they work once they have been damaged. Severe pain that occurs due to Guillain-Barre syndrome can last from a few weeks to over a year. The presence of other pre-existing psychological abnormalities or sensory disturbances may also be contributing factors to this symptom in affected individuals. Research has indicated there is a positive correlation between the presence of certain cerebrospinal proteins in the cerebrospinal fluid and severe pain as a symptom of Guillain-Barre syndrome.
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