Guide To The Symptoms And Treatment Of Crigler-Najjar Syndrome

Liver Transplant

A liver transplant can be potentially life-saving for individuals with Crigler-Najjar syndrome. This syndrome is caused by a liver that lacks the ability to convert unconjugated bilirubin into its conjugated form. If a patient is given a healthy liver, their body will then have the ability to conjugate and remove bilirubin from the blood.

Though a new liver removes the symptoms of Crigler-Najjar syndrome, it's important to note patients will still have the gene mutation that causes the liver issues, and they may pass it on to children they have. Patients who undergo successful liver transplants no longer need to use phototherapy, and they can function in day-to-day life without worrying about brain damage or death from the illness.