What Causes Restless Leg Syndrome?

Parkinson's Disease

Photo Credit: Dreamstime

Parkinson's disease is a medical condition related to abnormal functioning in the basal ganglia's dopamine pathways. This is important to note as there is a decent amount of evidence suggesting restless leg syndrome is related to a dysfunction of the basal ganglia and its use of dopamine, which is a chemical necessary to have smooth muscle activity. A disruption in the basal ganglia can result in jerky or otherwise involuntary movements. Involuntary movements are hallmark symptoms of both Parkinson's disease as well as restless leg syndrome, which is why Parkinson's disease patients are at an increased risk of developing the latter.

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