Risk Factors And Causes For A Pheochromocytoma

Neurofibromatosis 1

Neurofibromatosis 1 is a condition that causes multiple tumors around the body. The condition was formerly known as both von Recklinghausen neurofibromatosis and peripheral neurofibromatosis. Tumors are present in the optic nerve, and patients also have many skin tumors; these are known as neurofibromas. They typically occur on or just under the skin. Patients may also notice the presence of pigmented skin spots. For example, freckles may be observed in the groin or armpits, and there may be many light brown spots, also known as cafe au lait spots. Generally, neurofibromatosis is a benign condition, and type 1 typically appears in childhood. Neurofibromatosis 1 is the most common form, and it can cause bone deformities and learning difficulties in addition to elevated blood pressure. Scoliosis is the most common form of bone deformity with this condition, and learning difficulties are present in approximately fifty percent of patients.

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Von Hippel-Lindau Disease

Von Hippel-Lindau disease is an inherited disease that causes benign tumors and cysts at several locations throughout the body. Common tumor sites include the kidneys, pancreas, brain, and spinal cord. While the tumors are almost always benign, those that occur on the kidneys or pancreas have a higher risk of becoming malignant. Symptoms vary according to the location of tumors and include headaches, difficulty with balance and walking, vision problems, limb weakness, hypertension, and dizziness. A genetic test can confirm the presence of this condition, and both surgery and radiation are common treatment options. The prevalence of von Hippel-Lindau disease is approximately one in thirty thousand individuals. Due to the rarity of this cancer, patients are advised to be treated by a specialist medical team familiar with this particular condition.

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