Signs Of Paroxysmal Nocturnal Hemoglobinuria

Bruising And Bleeding

A patient diagnosed with paroxysmal nocturnal hemoglobinuria usually will have bone marrow that does not function properly. Bone marrow is responsible for creating red blood cells, white blood cells that help fight infection, and platelets. Without enough platelets, bruising and bleeding are more likely to occur. The low levels of platelets, or thrombocytopenia, can also lead to spontaneous bleeding. This malfunction, combined with some of the extensive organ damage that can occur with paroxysmal nocturnal hemoglobinuria, can lead to excessive bruising and bleeding.