11 Subtle Clues You Can Spot to Catch PVD Before It Progresses

9. Muscle Weakness or Fatigue

Muscles are great at telling us what they need—sometimes with soreness, other times with fatigue. If your lower legs start to feel unusually tired or weak during activities you once handled easily, it’s not just a sign of aging. As PVD limits blood flow, muscles may tire out sooner, especially during walking, climbing stairs, or standing. You might notice you need more breaks, or you avoid certain errands because your legs simply don’t want to keep up. This isn’t a sign of laziness or “falling behind,” just another voice in your body’s chorus of early clues. Try to distinguish between general tiredness and this specific, activity-related weakness. Over time, small adjustments—like shorter walks or varying your pace—can support your stamina, but don’t hesitate to talk with your care team about strategies that keep you feeling strong and capable.

10. Changes in Toenail Growth or Color

Our nails are surprisingly good storytellers when it comes to health. Slower-growing, thickened, or discolored toenails can show up when blood flow to the toes isn’t as strong as it used to be. You might notice new ridges, changes in thickness, or a nail that seems yellowish or dull. While nail changes often happen gradually and can have many causes—like shoes that fit poorly or fungal infections—PVD is one more clue to consider when changes appear for no clear reason. Instead of worrying about cosmetic appeal, think of monitoring nails as another empowering habit. Checking toenails during routine self-care, trimming, or moisturizing can help you spot patterns that deserve a mention at your next appointment. Your provider can help determine if circulation issues are playing a role and guide you toward gentle, supportive next steps.