The 14 Overlooked Symptoms That Could Be Pointing to an Autoimmune Disorder

11. Muscle Weakness

If lifting everyday objects feels unexpectedly challenging, or if muscles tire quicker than they used to, you might wonder what’s changed. Muscle weakness is one of those symptoms that can sneak up gradually; one day, a routine walk becomes unusually taxing, or climbing stairs is noticeably harder. These shifts are often written off as “out of shape” or simply getting older. For people with autoimmune conditions, the immune system can target muscle fibers or disrupt nerves that control movement, leading to weakness and fatigue. It’s not always associated with pain or injury and may not be visible to others. If muscle changes are limiting what you love to do, it’s a fair—and even hopeful—question to ask whether your immune system is in need of gentle support.

12. Recurring Infections

Most of us get the occasional cold or minor infection, especially during seasonal shifts. However, if you’re finding that infections—like sinus congestion, urinary trouble, or minor skin sores—show up often or just never seem to resolve, your immune system may be signaling that it’s working overtime or misfiring. Persistent infections are sometimes a clue that immune defenses are worn down or confused by other threats. These recurring illnesses are rarely seen as connected to deeper issues and are often treated one-at-a-time, without looking at the bigger picture. If your body just can’t seem to shake off bugs, or if you’re constantly back at the doctor for new rounds of antibiotics, don’t brush it off as bad luck. Your immune system is trying its best, and it deserves a closer look.