The 14 Overlooked Symptoms That Could Be Pointing to an Autoimmune Disorder

13. Circulation Problems (Numbness, Cold Extremities)

Cold hands, cold feet, tingling, or numbness now and then often seem like small annoyances. But when these symptoms become frequent or don’t have an easy explanation—like sitting cross-legged or being out in the cold—they can be quiet evidence of vascular or nerve changes connected to autoimmunity. Conditions that affect blood flow or nerve function can quietly alter sensation and warmth without leaving obvious marks. If you notice hands and feet that don’t warm up easily, persistent tingling, or numb patches, these aren’t things to simply “tough out.” Your circulatory and nervous systems are working hard, and these symptoms can be part of the story your immune system is trying to tell.

14. Sensory Sensitivities

Lights suddenly seem too bright, sounds feel overwhelming, or everyday textures become uncomfortable—these subtle changes can be easy to dismiss or adapt around. Yet, enhanced sensitivities to sensory input are not uncommon in autoimmune conditions. Inflammation can affect nerves in ways that amplify routine sensations. It’s easy to assume you’re just “getting sensitive” or overreacting, but these shifts often have a medical basis. Trust your instincts—if the world feels louder, brighter, or more irritating than before, it’s not just your imagination. Noticing and mentioning these changes is valuable both for your comfort and for connecting the dots with a care team.