What Causes Uremia?

Enlarged Prostate

Having an enlarged prostate, as is the case in patients with prostatic hyperplasia, plays a direct role in the development of uremia. In the early stages, the condition causes mild obstruction in the urinary tract. During this stage, patients are still able to urinate, but it often takes longer than normal. As the condition progresses to the middle stage, the blockage worsens, causing resistance from the urethra and exceeding the bladder's capability to compensate. Patients may frequently feel the need to urinate, but be unable to do so. The urine in the bladder can thus not be discharged completely or in a timely fashion, which can cause urea to enter the bloodstream.