Natural Fixes for the Fatigue Caused by Low Cortisol Levels

15. Replenish with B Vitamins

B vitamins, especially B5 (pantothenic acid), B6, and B12, are crucial for adrenal health and cortisol production. These vitamins support energy metabolism and help your body respond effectively to stress. Low levels of B vitamins can leave you feeling drained, anxious, and sluggish. Load up on whole foods like eggs, salmon, leafy greens, legumes, and fortified grains—or consider a high-quality B-complex supplement. Regular replenishment helps your body better manage daily stressors and bounce back from fatigue. When cortisol is low, the B vitamins act as quiet but essential rebuilders behind the scenes.

16. Say No Without Guilt

One of the most draining habits for those with low cortisol is overcommitting. Constant “yeses” can deplete already taxed adrenal glands. Learning to say no—without guilt—is an underrated form of energy preservation. Boundaries reduce chronic stress, give your body space to rest, and protect your cortisol rhythm. Practice polite but firm declines, like “I’d love to, but I’m at capacity this week.” Saying no is not selfish—it’s restorative. It’s a way of honoring your bandwidth, allowing your system to recover and replenish instead of running on fumes.