Anti-Inflammatory Foods That Work Better Than Pills

27. Shiitake Mushrooms (Lentinans for Cellular Defense)

High angle of brown beech mushrooms native to Asian countries placed on beige background. Photo Credit: Pexels @Laker

While functional mushrooms are mentioned, Shiitake mushrooms specifically contain a unique polysaccharide called Lentinan. Unlike the general beta-glucans in other varieties, Lentinan has been extensively studied for its ability to enhance the body's immune surveillance—meaning it helps the body identify and resolve issues without triggering a harmful, widespread inflammatory flare-up. Shiitake also offers a savory source of B vitamins and copper, nutrients that are vital for cellular energy and repair. Incorporate both fresh and dried shiitake mushrooms into broths and stir-fries for their deep umami flavor and their targeted, cellular-level defense against chronic inflammation.

28. Ginger Root (The COX and LOX Dual Inhibitor)

Close-up of fresh ginger root with sliced pieces and ginger powder spilled from a metal container. Photo Credit: Pexels @Pixabay

Ginger is a classic, but its power lies in its dual-action mechanism that goes beyond simple soothing. The active compounds, gingerols and shogaols, are unique in their ability to inhibit both the COX and LOX inflammatory pathways in the body—the same targets of many prescription and over-the-counter anti-inflammatory drugs. This simultaneous attack makes ginger exceptionally effective at easing joint pain and muscle soreness. Unlike general anti-inflammatories, ginger also actively supports gut motility, helping to clear toxins and waste that can otherwise fuel systemic inflammation. Enjoy it steeped in hot water, grated fresh into dressings, or crystallized (in moderation).

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