Anti-Inflammatory Foods That Work Better Than Pills

37. Oyster Mushrooms: Ergothioneine and Beta-Glucan

A close-up view of various dried wild mushrooms on a fabric surface, showcasing their unique textures. Photo Credit: Pexels @Leeloo The First

Oyster mushrooms are an overlooked culinary fungus providing a synergistic defense. They offer Beta-glucans (for immune modulation) and high levels of Ergothioneine. Ergothioneine is a unique, sulfur-containing antioxidant that the body actively transports into cells and mitochondria, specifically protecting these energy centers from the oxidative stress and damage that ignites inflammation. This targeted delivery system makes Oyster mushrooms an exceptional, accessible food for long-term cellular resilience. Sauté them lightly with olive oil and garlic, or add them to soups for an umami-rich, protective meal component.

38. Guava: Quercetin and Vitamin C in High Fiber

From above crop anonymous female with knife cutting fresh ripe fruits of guava on wooden chopping board on pink background. Photo Credit: Pexels @Any Lane

Guava is a tropical fruit that delivers a powerful, unique defense because it can be consumed whole (skin and all), maximizing its structural and chemical benefits. It is one of the best food sources of Vitamin C and is rich in the flavonoid Quercetin. This high-fiber, low-acidity structure ensures the Quercetin and Vitamin C are released slowly, maximizing their ability to quench free radicals and stabilize mast cells, thereby reducing histamine-driven inflammation. Eating fresh guava provides a slow-release, triple-action defense system that supports gut balance and reduces systemic inflammatory flares.

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