Signs Your Gut Microbiome is Out of Whack (And How to Fix It)

21. Sensitivity to Smells or Chemicals

Young woman pinching nose, feeling bad smell or discomfort. Photo Credit: Envato @GSR-PhotoStudio

If perfumes, cleaning products, or even everyday foods suddenly overwhelm your senses, it might not just be allergies—it could be your gut. A compromised microbiome can reduce your body’s ability to detoxify efficiently, making it hypersensitive to external stimuli. This chemical sensitivity is often linked to increased gut permeability ("leaky gut") and poor liver-gut axis communication. To rebuild resilience, support your gut and detox pathways with cruciferous vegetables, fiber, and plenty of hydration. Adding glutathione-rich foods like avocados and asparagus can also help your system manage chemical exposures more smoothly.

22. Nail Changes or Brittleness

Close-up of brittle nails. Damage to nail after using shellac or gel polish. Peeling on the nails. Photo Credit: Envato @AlenaIvochkina

Peeling, ridged, or brittle nails can signal nutrient malabsorption—and the gut is ground zero for that process. When your microbiome is compromised, you may struggle to absorb key vitamins like biotin, iron, zinc, and protein—all critical for nail strength. Instead of reaching for topical solutions, start with your gut. A diet rich in fermented foods, healthy fats, and collagen-boosting nutrients like vitamin C can support gut lining repair and improve nutrient uptake. Over time, as your microbiome heals, your nails will too—stronger, smoother, and more resilient.

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