Hidden Red Flags: Early Warning Signs Your Liver Might Be Under Stress

59. Unexplained Edema in the Testicles or Scrotum

While general swelling in the legs and ankles (edema) is a known symptom of liver issues, a more specific and less common sign in men can be unexplained swelling in the testicles or scrotum. This occurs when the liver's ability to produce albumin is severely compromised, causing fluid to accumulate in the lowest parts of the body due to gravity. This can be an early and specific warning sign of advanced liver disease, such as cirrhosis. If you notice this type of swelling, especially without a clear injury, it's a serious physical cue that your liver is no longer managing your body's fluid balance and requires immediate medical attention.

60. Spontaneous Itching on the Soles of the Feet or Palms

A specific and telling sign is when the itching is localized to the soles of the feet and the palms of the hands. This specific symptom is often associated with the buildup of bile salts in the skin, which is a key sign of a compromised liver and bile duct function. Unlike a typical rash or allergic reaction, this itching has no visible cause. This specific localization is an important and often overlooked clue that the liver is struggling to process bile and may indicate a condition like cholestasis.