Causes Of Acute Nephritis

Broken Abscesses

An individual develops an abscess in their kidney when an infection travels through their blood from a primary source in the body and colonizes in the perirenal space and the small filters of the kidney. The bacteria induce an inflammatory response by the patient's immune system, where an influx of white blood cells and other inflammatory substances are summoned to the site of the infection. These components coagulate in a capsular fashion and have the potential to develop into a fluid-filled or lobular abscess in the kidney.

A kidney abscess can rupture as a result of internal or external trauma to the area, allowing the infective contents and bacterial byproducts to spill and come into direct contact with the surrounding kidney tissues. These substances damage the structure and functionality of the small filters in the kidneys, which can induce acute nephritis.

Taking Too Many Anti-Inflammatories And Pain Relievers

Anti-inflammatory medications and pain relievers are effective at treating pain and reducing fevers, but excessive use can cause the development of acute nephritis. Most of these medications should not be used for longer than ten days to treat pain, and more than three days to treat a fever. Every medication ingested will pass through the kidneys as they filter toxins, wastes, and excess fluids from the blood. These medications cause the kidneys to have to work harder to clear the drugs and their byproducts from the blood.

When the kidneys carry this burden of being overworked for a long time, the kidney tissues can incur damage. The damage done to the filters in the kidneys can produce inflammation that the immune system and healing mechanisms work tirelessly to repair. As kidney function reduces over time from the excessive use of anti-inflammatory medications and pain relievers, the organ becomes less capable of upholding a burdensome workload and is more vulnerable to inflammation and acute nephritis.