Little-Known Signs Your Thyroid Is Out of Whack

17. Carpal Tunnel Syndrome: A Nerve-Related Signal

Office workers are particularly prone to carpal tunnel syndrome. Photo Credit: Envato @YuriArcursPeopleimages

Tingling, numbness, or weakness in the hands—particularly in the thumb, index, or middle fingers—can be more than a repetitive strain issue. Carpal tunnel syndrome is surprisingly common in those with untreated hypothyroidism. The reason? Thyroid hormone deficiency can lead to fluid retention and swelling in connective tissues, which puts pressure on the median nerve in the wrist. If you're developing nerve pain without repetitive stress, or your symptoms worsen at night, a thyroid check may be in order. Treating the underlying thyroid imbalance often alleviates the nerve compression.

18. Puffy Face or Swollen Eyes: The Inflammatory Signal

Sleepless African woman looking her face in the mirror and worry about dark circles under eyes. Photo Credit: Envato @nikolast1

A subtly swollen face or persistent puffiness around the eyes might be your thyroid waving a red flag. In hypothyroidism, slowed circulation and increased fluid retention can lead to visible swelling in the face, lips, or eyelids. For hyperthyroid individuals, particularly those with Graves’ disease, inflammation behind the eyes can cause bulging (exophthalmos) or discomfort. These physical cues are easy to overlook or attribute to poor sleep, allergies, or salty meals—but they can be some of the most visible markers of thyroid imbalance. If puffiness becomes persistent or noticeable in photos, it’s time to look deeper.

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